Endocrine Abstracts

Introduction: For the clinical diagnosis of heterozygous familial hypercholesterolemia (HeFH) validated algorithms are used, with the Dutch Lipid Clinic Network (DLCN) Criteria being the most recommended in our environment. One of the items that scores for the system proposed by the DLCN is the value of LDL cholesterol. However, LDLc levels can be distorted by lipoprotein a (Lpa(a)) levels.Objective: To analyze the change in the validity of the DLCN crit...

Introduction: Biotin is a water-soluble vitamin involved in several and important metabolic processes, recommended daily intake for adults is 30–100 μg/day and normal plasma concentrations are 0.4–1.2 ng/day. Nowadays biotin is being used in inherited metabolic diseases, multiple sclerosis and as a supplement in, over the counter multivitamins widely used for common hair and skin problems. The supraphysiologic biotin intake has produced emerging problems with bi...